Product Name: PAC-1
Subtitle: Procaspase-3 activator
Biological Activity: Biological Activity of PAC-1Procaspase-activating compound; activates procaspase-3 to produce caspase-3 (EC50 = 0.22 μM). Also activates procaspase-7 in a less efficient manner (EC50 = 4.5 μM). Pro-apoptotic; induces apoptosis in both cancerous and
SMLES: C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)C1=O
CAS NO: 1375465-91-0
Standard In CHIKey: Protease_Inhibitor_Cocktail inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C23H28N4O2
M.Wt: 392.49
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/26/6/479
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 75 mM in 1eq. HCl and to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 4-(Phenylmethyl)-1-piperazineacetic acid [[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide