Product Name: PCI-32765 (Ibrutinib)
Subtitle: Brutons tyrosine kinase (BTK) inhibitor
Biological Activity: Biological Activity of PCI-32765 (Ibrutinib)Description Ibrutinib is a potent and highly selective inhibitor of Btk with IC50 of 0.5 nM, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Targets Btk
SMLES: C=CC(=O)N1CCCC(C1)N2C3=C(C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)C(=NC=N3)N
CAS NO: 379231-04-6
Standard In CHIKey: Cholecystokinin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H24N6O2
M.Wt: 440.5
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/2/531
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide