Product Name: PD 146176
Subtitle:
Biological Activity: Biological Activity of PD 146176Specific, non-competitve 15-lipoxygenase (15-LOX) inhibitor (Ki = 197nM) that has no demonstrable effect on 5-LOX, 12-LOX, COX-1 or COX-2 (IC50 = 0.54 μM for 15-LOX in rabbit reticulocytes). Lacks non-specific antioxid
SMLES: C12=C(C3=CC=CC=C3SC2)NC4=CC=CC=C14
CAS NO: 73232-52-7
Standard In CHIKey: ZGOOPZVQMLHPFM-UHFFFAOYSA-NPKA inhibitors
Standard InChI: InChI=1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2
Typrof Compound:
Appearance:
Formula: C15H11NS
M.Wt: 237.32
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/2/750
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole