Product Name: PD98059
Subtitle: MEK inhibitor,selective and reversible
Biological Activity: Biological Activity of PD98059Inhibitor of mitogen-activated protein kinase kinase (MKK / MEK). Acts by binding to the inactivated form of MEK, thereby preventing its phosphorylation by cRAF or MEK kinase (IC50 = 2-7 μM). Inhibits cell growth and proli
SMLES: COc1cccc(c1N)c2cc(=O)c3ccccc3o2
CAS NO: 899805-25-5
Standard In CHIKey: QFWCYNPOPKQOKV-UHFFFAOYSA-NWnt/Hedgehog/Notch_Compound_Library inhibitors
Standard InChI: InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3
Typrof Compound:
Appearance:
Formula: C16H13NO3
M.Wt: 267.28
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/146
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in DMSO and to 5 mM in ethanol
Storage: Store at RT
Purity: >98%
Chemical Name: 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one