Product Name: PI-103 Hydrochloride
Subtitle: DNA-PK/PI 3-kinase/mTOR inhibitor
Biological Activity: Biological Activity of PI-103 HydrochlorideInhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ~ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110&ga
SMLES: C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl
CAS NO: 209216-23-9
Standard In CHIKey: DNA Alkylator_Crosslinker inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H17ClN4O3
M.Wt: 384.82
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/587
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: 3-[4-(4-Morpholinylpyrido[3,2:4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride