Product Name: PI-103
Subtitle: Class I PI3K, mTOR and DNA-PK inhibitor
Biological Activity: Biological Activity of PI-103Description PI-103 is a multi-targeted inhibitor of PI3K for p110α/β/δ/γ with IC50 of 2 nM/3 nM/3 nM/15 nM, less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. Targets Cell, 2013, 153(4):840-54 p110β p110δ p110γ mT
SMLES: C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O
CAS NO: 1206161-97-8
Standard In CHIKey: Influenza Virus inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H16N4O3
M.Wt: 348.36
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/1/411
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol