Product Name: PR-619
Subtitle: Deubiquitylating enzymes (DBUs) inhibitor
Biological Activity: Biological Activity of PR-619Broad spectrum, reversible DUB inhibitor. Exhibits limited activity against other proteases. Induces accumulation of polyubiquitinated proteins, but has no direct inhibitory effect on the proteasome. Cytotoxic in HEK293T and c
SMLES: C1=C(C(=NC(=C1SC#N)N)N)SC#N
CAS NO: 592542-60-4
Standard In CHIKey: Endocrinology inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C7H5N5S2
M.Wt: 223.28
General Tips: for obtaining a higher concentration: Please warm the tube at 37℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/26/1/49
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: 2,6-Diamino-3,5-dithiocyanopyridine