Product Name: PRIMA-1MET
Subtitle: Restore mutant p53 activity, induce BAX and PUMA
Biological Activity: Biological Activity of PRIMA-1METMethylated derivative of PRIMA-1. Restores mutant activity p53 activity. Acts synergistically with chemotherapeutic agents to inhibit tumor cell proliferation.
SMLES: COCC1(C(=O)C2CCN1CC2)CO
CAS NO: 55721-11-4
Standard In CHIKey: Smad_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C10H17NO3
M.Wt: 199.25
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/26/6/421
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one