Product Name: PRT 4165
Subtitle:
Biological Activity: Biological Activity of PRT 4165Inhibitor of Bmi1/Ring1A, subunits of the polycomb repressive complex 1 (PRC1); inhibits self-ubiquitination (IC50 = 3.9 μM) but does not increase cellular levels of either subunit. Prevents Bmi1/Ring1A-mediated ubiquit
SMLES: O=C1C2=CC=CC=C2C(/C1=C/C3=CC=CN=C3)=O
CAS NO: 1311367-27-7
Standard In CHIKey: OMHZFEWYVFWVLI-UHFFFAOYSA-NMetabolism/Protease_Compound_Library inhibitors
Standard InChI: InChI=1S/C15H9NO2/c17-14-11-5-1-2-6-12(11)15(18)13(14)8-10-4-3-7-16-9-10/h1-9H
Typrof Compound:
Appearance:
Formula: C15H9NO2
M.Wt: 235.24
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/26/5/347
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 5 mM in 1eq. HCl with gentle warming
Storage: Store at +4℃
Purity: >98%
Chemical Name: 2-(3-Pyridinylmethylene)-1H-Indene-1,3(2H)-dione