Product Name: Pelitinib (EKB-569)
Subtitle: EGFR inhibitor,potent and irreversible
Biological Activity: Biological Activity of Pelitinib (EKB-569)Description Pelitinib is a potent irreversible inhibitor of EGFR with IC50 value of 38.5 nM. Targets EGFR IC50 38.5 nM
SMLES: CCOc1cc2c(cc1NC(=O)/C=C/CN(C)C)c(c(cn2)C#N)Nc3ccc(c(c3)Cl)F
CAS NO: 1352226-88-0
Standard In CHIKey: WVUNYSQLFKLYNI-AATRIKPKSA-NHippo MST) inhibitors
Standard InChI: InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+
Typrof Compound:
Appearance:
Formula: C24H23ClFN5O2
M.Wt: 467.92
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/1063
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: pelitinib