Product Name: R788 disodium
Subtitle: Syk inhibitor,ATP competitive and potent
Biological Activity: Biological Activity of R788 disodiumDescription R788 (Fostamatinib) disodium, a prodrug of the active metabolite R406, is an inhibitor of Syk with IC50 of 41 nM. Targets Syk IC50 41 nM
SMLES: CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.[Na+].[Na+]
CAS NO: 1285515-21-0
Standard In CHIKey: Motilin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C23H24FN6Na2O9P
M.Wt: 624.42
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/274/3/1463
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Limited solubility
Storage:
Purity: >98%
Chemical Name: disodium;[6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl phosphate