Product Name: RS 504393
Subtitle: CCR2 chemokine receptor antagonist
Biological Activity: Biological Activity of RS 504393Extremely selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and > 100 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC50 = 330 nM) and isch
SMLES: CC1=CC2=C(C=C1)NC(=O)OC23CCN(CC3)CCC4=C(OC(=N4)C5=CC=CC=C5)C
CAS NO: 1610537-15-9
Standard In CHIKey: Serotonin Transporter inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C25H27N3O3
M.Wt: 417.5
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/2/484
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 6-Methyl-1-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4-piperidin]-2(1H)-one