Product Name: Roflumilast
Subtitle: PDE-4 inhibitor
Biological Activity: Biological Activity of Roflumilast 1. Roflumilast is a phosphodiesterase 4 inhibitor that may improve lung function and reduce the frequency of exacerbations in patients with COPD. 2. Suppression of hematological and immunological markers of inflammation
SMLES: FC(F)Oc1ccc(cc1OCC2CC2)C(=O)Nc3c(Cl)cncc3Cl
CAS NO: 501437-28-1
Standard In CHIKey: MNDBXUUTURYVHR-UHFFFAOYSA-NAdenylate Cyclase inhibitors
Standard InChI: InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)
Typrof Compound: Miscellaneous
Appearance: Powder
Formula: C17H14Cl2F2N2O3
M.Wt: 403.21
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/2/809
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: ≥98%
Chemical Name: 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide