Product Name: Rotigotine hydrochloride
Subtitle: Agonist of dopamine D2/D3 receptor
Biological Activity: Biological Activity of Rotigotine hydrochlorideDopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Also has significant affinity for 5-HT1A and adrenergic α2B receptors. Exhibits antiparkinsonian acitivity.
SMLES: CCCN(CCC1=CC=CS1)C2CCC3=C(C2)C=CC=C3O.Cl
CAS NO: 62-13-5
Standard In CHIKey: CEXBONHIOKGWNU-NTISSMGPSA-NLRRK2 inhibitors
Standard InChI: InChI=1S/C19H25NOS.ClH/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21;/h3-7,13,16,21H,2,8-12,14H2,1H3;1H/t16-;/m0./s1
Typrof Compound:
Appearance:
Formula: C19H26ClNOS
M.Wt: 351.93
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/268/1/110
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in water with gentle warming and to 100 mM in DMSO
Storage: Desiccate at RT
Purity: >98%
Chemical Name: (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol hydrochloride