Product Name: SB 239063
Subtitle: P38 MAP kinase inhibitor
Biological Activity: Biological Activity of SB 239063Potent and selective p38 MAP kinase inhibitor (IC50 = 44 nM for p38α). Displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580. Reduces inflammatory cytokine producti
SMLES: COC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F
CAS NO: 1337531-36-8
Standard In CHIKey: HCV inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H21FN4O2
M.Wt: 368.41
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/300
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 10 mM in DMSO with gentle warming
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: trans-4-[4-(4-Fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]cyclohexanol