Product Name: SB705498
Subtitle: TRPV1 antagonist,potent and selective
Biological Activity: Biological Activity of SB705498Description SB705498 is an antagonist of TRPV1 with IC50 values of 3 nM, 0.1 nM and 6 nM for hTRPV1, antagonizes capsaicin, acid and heat activation of TRPV1,respectively. Targets hTRPV1 IC50 3 nM
SMLES: C1CN(CC1NC(=O)NC2=CC=CC=C2Br)C3=NC=C(C=C3)C(F)(F)F
CAS NO: 1219810-16-8
Standard In CHIKey: Oxytocin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H16BrF3N4O
M.Wt: 429.23
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/258/3/945
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 1-(2-bromophenyl)-3-[(3R)-1-[5-(trifluoromethyl)pyridin-2-yl]pyrrolidin-3-yl]urea