Product Name: SGX-523
Subtitle: MET inibitor, highly selective, ATP-competitive
Biological Activity: Biological Activity of SGX-523Potent and selective c-MET kinase inhibitor (IC50 = 4nM). Exhibits minimal inhibition against a panel of 213 other protein kinases (at 1 μM). Suppresses growth of tumor xenografts derived from human glioblastoma, lung an
SMLES: Cn1cc(cn1)c2ccc3nnc(n3n2)Sc4ccc5c(c4)cccn5
CAS NO: 377727-87-2
Standard In CHIKey: MyD88 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H13N7S
M.Wt: 359.41
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/1/164
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 6-[[6-(1-Methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-b]pyridazin-3-yl]thio]quinoline