Product Name: SNX-2112
Subtitle: Hsp90 inhibitor,ATP-competitve,potent and selective
Biological Activity: Biological Activity of SNX-2112Description SNX-2112 is an ATP-competitve inhibitor of Hsp90α and Hsp90β with Ka values of both 30 nM. Targets Hsp90α Hsp90β IC50 30 nM (Ka) 30 nM (Ka)
SMLES: CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)O)C(F)(F)F)C
CAS NO: 155683-00-4
Standard In CHIKey: EAAT2 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C23H27F3N4O3
M.Wt: 464.48
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/271/1/7
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-hydroxycyclohexyl)amino]benzamide