Product Name: SP 600125
Subtitle: JNK1/2/3 inhibitor
Biological Activity: Biological Activity of SP 600125Selective JNK inhibitor. Competitively and reversibly inhibits JNK1, 2 and 3 (IC50 = 40 – 90 nM) with negligible activity at ERK2, p38β and a range of enzymes. Active in vivo. Exhibits reduced selectivity over other protein
SMLES: O=C1C2=CC=CC3=C2C(C4=CC=CC=C41)=NN3
CAS NO: 924416-43-3
Standard In CHIKey: ACPOUJIDANTYHO-UHFFFAOYSA-NAntibody-drug Conjugate_ADC Related inhibitors
Standard InChI: InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)
Typrof Compound:
Appearance:
Formula: C14H8N2O
M.Wt: 220.23
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/346
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 5 mM in ethanol with gentle warming and to 100 mM in DMSO
Storage: Desiccate at -20℃
Purity: >98%
Chemical Name: Anthra[1-9-cd]pyrazol-6(2H)-one