Product Name: Skepinone-L
Subtitle: P38-MAPK inhibitor,potent and selective
Biological Activity: Biological Activity of Skepinone-LDescription Skepinone-L is a selective inhibitor of p38 mitogen-activated protein kinase (MAPK) and TNF-α with IC50 values of 5 nM and 40 nM, respectively. Targets p38-MAPK TNF-α IC50 5 nM 40 nM
SMLES: C1CC2=C(C=CC(=C2)NC3=C(C=C(C=C3)F)F)C(=O)C4=C1C=CC(=C4)OCC(CO)O
CAS NO: 1082744-20-4
Standard In CHIKey: Influenza Virus inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H21F2NO4
M.Wt: 425.42
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/1/318
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 3-(2,4-difluoroanilino)-9-[(2R)-2,3-dihydroxypropoxy]-5,6-dihydrodibenzo[3,1-[7]annulen-11-one