Product Name: Sorafenib
Subtitle: Raf kinases and tyrosine kinases inhibitor
Biological Activity: Biological Activity of Sorafenib 1. Sorafenib together with inhibitors of the β-catenin pathway might be an effective tool in the treatment of pediatric HCC. 2. Cyproheptadine may significantly improve survival outcomes of Sorafenib-treated advanced he
SMLES: CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1
CAS NO: 939981-39-2
Standard In CHIKey: MLDQJTXFUGDVEO-UHFFFAOYSA-NIFNAR inhibitors
Standard InChI: InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
Typrof Compound: Alkaloids
Appearance: Powder
Formula: C21H16ClF3N4O3
M.Wt: 464.83
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/259/1/146
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: ≥98%
Chemical Name: 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide