Product Name: Spautin-1
Subtitle: Novel autophagy inhibitor
Biological Activity: Biological Activity of Spautin-1Inhibitor of autophagy; inhibits USP10 and USP13 activity (IC50 values are 0.6 and 0.7 μM respectively) and promotes degradation of Vps34 (class III PI 3-kinase) complexes. Selectively promotes apoptosis of cancer cell
SMLES: FC1=CC=C(C/N=C2C3=C(N=CN/2)C=CC(F)=C3)C=C1
CAS NO: 222631-44-9
Standard In CHIKey: Natural_Product_Library_ inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C15H11F2N3
M.Wt: 271.26
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/26/5/359
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 6-Fluoro-N-[(4-Fluorophenyl)methyl]-4-quinazolinamine