Product Name: Sunitinib
Subtitle: RTK inhibitor
Biological Activity: Biological Activity of SunitinibDescription Sunitinib is an oral, multi-targeted and small-molecule inhibitor of receptor tyrosine kinase (RTK). Targets VEGFR-1 VEGFR-2 VEGFR3 PDGFRα PDGFRβ c-kit IC50 4 nM 69 nM 39 nM 1-10 nM
SMLES: CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
CAS NO: 1173022-16-6
Standard In CHIKey: WINHZLLDWRZWRT-ATVHPVEESA-NSPHK inhibitors
Standard InChI: InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-
Typrof Compound:
Appearance:
Formula: C22H27FN4O2
M.Wt: 398.47
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/1/194
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO
Storage:
Purity: >98%
Chemical Name: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide