Product Name: TAK-438
Subtitle: Blocker of potassium-competitive acid
Biological Activity: Biological Activity of TAK-438Description TAK-438 is a potassium-competitive acid blocker (P-CAB) of H,K-ATPase with IC50 value of 19 nM. Targets H,K-ATPase IC50 19 nM
SMLES: CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=CC(=O)O)C(=O)O
CAS NO: 1195765-45-7
Standard In CHIKey: Mps1 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H16FN3O2S.C4H4O4
M.Wt: 461.46
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/258/2/588
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: (E)-but-2-enedioic acid;1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine