Product Name: TAK-715
Subtitle: p38 MAPK inhibitor
Biological Activity: Biological Activity of TAK-715Inhibitor of p38 MAPK (IC50 = 7.1 nM for p38 MAPKα). Also inhibits Wnt-3a-stimulated β-catenin signaling. Inhibits 22 kinases by more than 80%, including CK1δ/ε. Anti-inflammatory and anti-rheumatoid arthr
SMLES: CCC1=NC(=C(S1)C2=CC(=NC=C2)NC(=O)C3=CC=CC=C3)C4=CC(=CC=C4)C
CAS NO: 1448671-31-5
Standard In CHIKey: LRRK2 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H21N3OS
M.Wt: 399.52
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/255/2/403
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 50 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-[4-[2-Ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide