Product Name: U-104
Subtitle: CAIX inhibitor
Biological Activity: Biological Activity of U-104Potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA IX, CA I and CA II respectively in MDA-MB-231 cells). Inhibits tumor metastasis in the rat 4T1 metastasis model.
SMLES: C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)S(=O)(=O)N)F
CAS NO: 898563-00-3
Standard In CHIKey: GPR119 inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C13H12FN3O3S
M.Wt: 309.32
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/266/2/904
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 4-[[[(4-Fluorophenyl)amino]carbonyl]amino]-benzesulfonamide