Product Name: VS-5584 (SB2343)
Subtitle: MTOR/P13K inhibitor,potent and selective
Biological Activity: Biological Activity of VS-5584 (SB2343)Description VS-5584 (SB2343) is a potent and selective dual inhibitor of PI3K/mTOR inhibitor for mTOR, PI3Kα/β/δ/γ with IC50 of 3.4 nM and 2.6-21 nM, respectively. Targets mTOR PI3Kα PI3Kα-H1047 PI3Kβ PI3K
SMLES: CC1=NC2=C(N=C(N=C2N1C(C)C)N3CCOCC3)C4=CN=C(N=C4)N
CAS NO: 1092351-67-1
Standard In CHIKey: G-quadruplex inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H22N8O
M.Wt: 354.41
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/621
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 5-(8-methyl-2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine