Product Name: VU0152100
Subtitle: M4 receptor allosteric modulators
Biological Activity: Biological Activity of VU0152100Selective positive allosteric modulator of M4 muscarinic acetylcholine receptors (mAChRs) (EC50 = 380 nM). Induces 21-fold shift in ACh potency at M4 receptor. Displays no activity at other mAChR subtypes.
SMLES: CC1=CC(=NC2=C1C(=C(S2)C(=O)NCC3=CC=C(C=C3)OC)N)C
CAS NO: 130477-52-0
Standard In CHIKey: Angiotensin Receptor inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H19N3O2S
M.Wt: 341.43
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/268/1/495
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 3-Amino-N-(4-methoxybenzyl)-4,6-dimethylthieno[2,3-b]pyridine carboxamide