Product Name: WR 1065
Subtitle: P53/p21waf-1/MDM2 activator
Biological Activity: Biological Activity of WR 1065Cell-permeable reactive oxygen species scavenger that activates p53 through a JNK-dependent signaling pathway. Activates p21waf-1 and MDM2, represses transcription of Myc and thymidine kinase, and inhibits DNA topoisomerase I
SMLES: C(CN)CNCCS.Cl.Cl
CAS NO: 1262618-39-2
Standard In CHIKey: XDRLRDHLCIFZIW-UHFFFAOYSA-NInhibitor_Kit inhibitors
Standard InChI: InChI=1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H
Typrof Compound:
Appearance:
Formula: C5H14N2S.2HCl
M.Wt: 207.16
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/26/6/469
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
Storage: Desiccate at -20℃
Purity: >98%
Chemical Name: 2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride