Product Name: WZ8040
Subtitle: EGFR T790M inhibitor,irreversible amd potent
Biological Activity: Biological Activity of WZ8040Description WZ8040 is an irreversible inhibitor of EGFR T790M with IC50 value of <10nM. Targets EGFR T790M IC50 <10nM
SMLES: CN1CCN(CC1)c2ccc(cc2)Nc3ncc(c(n3)Sc4cccc(c4)NC(=O)C=C)Cl
CAS NO: 379231-04-6
Standard In CHIKey: Hedgehog inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H25ClN6OS
M.Wt: 481.01
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/254/3/1054
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N-{3-[(5-Chloro-2-{[4-(4-methyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)sulfanyl]phenyl}acrylamide