Product Name: YIL 781
Subtitle:
Biological Activity: Biological Activity of YIL 781Ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM). Displays no significant affinity for the motilin receptor (Ki = 6 μM). Blocks the effects of ghrelin on insulin secretion both in vivo and in vitro. Improves glucose ho
SMLES: FC1=CC=C(C=C1)OC2=CC=C3N=C(C)N(C(C3=C2)=O)C[C@@H]4CN(C(C)C)CCC4.Cl
CAS NO: 1628428-01-2
Standard In CHIKey: Thymidylate Synthase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H28FN3O2.HCl
M.Wt: 445.96
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/266/1/456
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in water
Storage: Desiccate at RT
Purity: >98%
Chemical Name: 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone