Product Name: ZSTK474
Subtitle: Potent PI3K inhibitor
Biological Activity: Biological Activity of ZSTK474Description ZSTK474 is inhibitor of class I PI3K isoforms with an IC50 of 37 nM. Targets PI3Kδ PI3Kα PI3K PI3Kβ PI3Kγ IC50 4.6 nM 16 nM 37 nM 44 nM 49 nM
SMLES: C1COCCN1C2=NC(=NC(=N2)N3C4=CC=CC=C4N=C3C(F)F)N5CCOCC5
CAS NO: 1217486-61-7
Standard In CHIKey: Cytoskeleton inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C19H21F2N7O2
M.Wt: 417.41
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/257/2/774
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine