Towards the complementary role in evaluating microsomal liver function,Cmethacetin breath test might be a dependable diagnostic and followup test for patients with chronic liver disease. Disclosure of Interest: None declaredP Increasing FREQUENCY OF GRAMPOSITIVE COCCI IN SPONTANEOUS BACTERIAL PERITONITIS. A SINGLE CENTRE Practical experience C. Triantos,C. Grigoropoulou,N. Koukias,A. Zavitsanaki,M. Christofidou,I. Spiliotopoulou,C. Tsolias,V. Nikolopoulou,C. Karatza,K. Thomopoulos Gastroenterology Department,Basic Medicine Division,Microbiology Laboratory,University Hospital of Patras,Patras,Greece Speak to Email Address: nkoukiasgmail Introduction: Sponteneous bacterial peritonitis (SBP) in patients with hepatic cirrhosis is mainly related to gram damaging enterobacteriaceae. Current research have reported a modify in the epidemiology of microbes which are becoming isolated in SBP and an increased prevalence of gram good and multiresistant bacteria. Aims Approaches: Record the bacteria which have been isolated in the ascitic fluid of individuals with hepatic cirrhosis and their resistance in commonly made use of antibiotics. Good ascitic fluid cultures of cirrhotic sufferers which have been admitted in our hospital and also the respective antibiograms have already been retrospectively recorded. Outcomes: patients ( male) with hepatic cirrhosis with a median age of years had optimistic ascitic fluid culture. In cultures Gram positive bacteria happen to be isolated. In detail the isolated bacteria were: enterococcus spp. ,Escherichia coli ,streptococcus spp ,Klebsiella ,staphylococcus ,Proteasspp ,Enterobacter Acinetobacter ,Cronobacter ,Pseudomonas aurigonosa . Resistance to rd generation cephalosporines has been identified in out strains,in ciprofloxacine in out of and in ampicilline in out of . Conclusion: Gram bacteria happen to be isolatedin the majority of constructive ascitic fluid cultures. Resistance to AAT-007 rdgeneration cephalosporines and ciprofloxacine is frequent. Therapy should really be individualized in line with culture final results and sufferers characteristics. Disclosure of Interest: None declaredA P EARLY INPATIENT MANAGEMENT OF ALCOHOLRELATED LIVER Disease: Benefits OF A LIVER CARE BUNDLE To enhance Excellent OF CARE C. Mason,I. HuangDoran,M. McPhail,S. Peake,K. Monahan,C. Collins Department of Gastroenterology,West Middlesex University Hospital,London,United kingdom Introduction: The incidence of Alcohol Connected Liver Illness (ARLD) is rising inside the UK,as is its linked mortality. A recent National Confidential Enquiry into Patient Outcome and Death (NCEPOD) report highlighted recurring deficiencies inside the management of ARLD in UK hospitals as well as the British Society of Gastroenterology supplied guidance within the therapy of those patients throughout acute hospital admissions. Aims Strategies: Between August and October ,consecutive admissions of patients with ARLD to a district general hospital had been identified from discharge and mortality information. A liver care bundle (LCB) working with NCEPOD suggestions was generated. Case notes were analysed prior to institution of this LCB and reaudited following its inception from April to July PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/19389808 . Electronic referrals to specialist gastroenterology and dieticians formed part of the LCB,at the same time as a checklist of actions for the admitting physician. Final results: sufferers (median age years) had been identified initially with ARLD,of which ( had been male. Median Model for Endstage Liver Illness (MELD) score was (variety ). Post LCB institution a further cohort of sufferers studied w.