Sented within this study is often found in on-line repositories. The names on the repository/repositories and accession number(s) may be found beneath: ncbi.nlm.nih. gov; Dhps: OP279202-OP279230. Dhfr: OP279231-OP279259. Crt: MZ572585, MZ572586, MZ572588, MZ572598, MZ572603, MZ572604, MZ572610, MZ572611, MZ572619, MZ572624MZ572626, MZ572633, MZ572647, MZ572657, MZ572685, MZ572692, MZ572703, MZ572715, MZ572718-MZ572721, M Z5 72 7 26 , M Z 57 27 three 7, OP 2 79 26 0 -O P two 79 26 2. K1 three: MK877272, MK877273, MK877275, MK877286, MK877291, MK877292, MK877300, MK877301, MK877307, MK877308, MK877319, MK877324-MK877327, MK877333, MK877346, MK877357, MK877374, MK877392, MK877398, MK877412, MK877416-MK877419, MK877424, MK877436, OP297930. Mdr1-1: MZ572380, MZ572381, MZ572383, MZ572394, MZ572399, MZ572400, MZ572408, MZ572409, MZ572415, MZ572416, MZ572427, MZ572432-MZ572435, MZ572441, MZ572451, MZ572462, MZ572480, MZ572500, MZ572506, MZ572517, MZ572521-MZ572524, MZ572528, MZ572540, OP297931. Mdr1-2: MZ577631, MZ577632, MZ577634, MZ577645, MZ577650, MZ577651, MZ577659, MZ577660, MZ577666-MZ577668, MZ577683-MZ577686, MZ577692, MZ577702, MZ577713, MZ577731, MZ577751, MZ577757, MZ577768, MZ577772-MZ577775, MZ577779, MZ577791, OP297932.M-CSF Protein Source Ethics statementThe research involving human participants were reviewed and approved by Institutional Assessment Board, Shanglin People’s Hospital. The patients/participants supplied their written informed consent to take part in this study.Frontiers in Cellular and Infection Microbiologyfrontiersin.orgZhao et al.ten.3389/fcimb.2022.Author contributionsLC and ZY conceived the study. WZ, XXL, QY, MD, XSL, XW, WLZ, HZ, KS, and WYZ performed the experiments. WZ, XXL, QY, YA, LA, BA, ND-Q, and LC analyzed the data. LZ, MP, YQ, and YH collected the parasites. WZ, LC, and ZY wrote the very first drafts with the manuscript. All authors critically read and edited the manuscript. All authors read and authorized the final manuscript. All authors contributed for the short article and approved the submitted version.AcknowledgmentsThe authors thank all of the patients for volunteering to take part in the study.Conflict of interestThe authors declare that the analysis was carried out inside the absence of any commercial or monetary relationships that may very well be construed as a potential conflict of interest.FundingThis study was supported by the National Science Foundation of China (31860604 and U1802286), National Institutes of Wellness, USA (U19AI089672), main science and technology projects of Yunnan Province (2018ZF0081), and International Science and Technologies Cooperation-Yunnan International Science and Technology Cooperation Base (202003AE140004), along with the introduction of intellectual projects (202105AP130005 and YNZ201901921).SDF-1 alpha/CXCL12, Human (68a.a) YQ was supported by Guangxi Zhuang Autonomous Area Overall health Commission of Scientific Analysis Project (Z20190892).PMID:23800738 WZ was supported by the Education Department Fund of Yunnan Province (2019J1184).Research Project of Overall health Commission of Guangxi Zhuang Autonomous Area(ZA20221274).Publisher’s noteAll claims expressed within this report are solely these of your authors and don’t necessarily represent these of their affiliated organizations, or those with the publisher, the editors plus the reviewers. Any product that may well be evaluated in this post, or claim that may possibly be produced by its manufacturer, is not assured or endorsed by the publisher.Supplementary materialThe Supplementary Material for this short article might be identified on the web at: frontiersin.org/articl.