Name : Human A2AR Protein-VLP
Product Source :
Recombinant Human A2AR Protein-VLP is expressed from HEK293. It contains Met1-Ser412.[Accession | P29274]
Molecular Weight :
The target protein has a predicted MW of 45.5 kDa.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by HPLC
Formulation :
Supplied as 0.22μm filtered solution in PBS, 300mM L-Arginine (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
SEC-HPLC The purity of Human A2AR VLP is greater than 95% as determined by SEC-HPLC. ELISA Data Immobilized Human A2AR VLP at 10μg/ml (100μl/Well) on the plate. Dose response curve for Anti-A2AR Antibody, hFc Tag with the EC50 of 0.87μg/ml determined by ELISA.
Background :
Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expression of A2a adenosine receptor mRNA in cranial ganglia, carotid body, and intermediate lobe of the pituitary gland similarly suggests novel sites of adenosine action during development and in the adult.
Synonyms :
A2aR;Adenosine A2a R;ADORA 2;ADORA2;ADORA2A;RDC8
References & Citations :
Weaver DR. A2a adenosine receptor gene expression in developing rat brain. Brain Res Mol Brain Res. 1993 Dec;20(4):313-27. doi: 10.1016/0169-328x(93)90058-w. PMID: 8114618.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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