Name : Human FSH alpha&beta Protein

Product Source :
Recombinant Human FSH alpha&beta Protein is expressed from HEK293 with His tag at the C-terminus. It contains Ala25-Ser116 (FSH alpha) and Asn19-Glu129 (FSH beta).[Accession | P01215(FSH alpha)&P01225 (FSH beta)]

Molecular Weight :
The protein has a predicted MW of 10.20 kDa (FSH alpha) and 13.58 kDa (FSH beta). Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC

Formulation :
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).

Reconstitution :

Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Human FSH alpha&beta on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human FSH alpha&beta is greater than 95% as determined by SEC-HPLC.

Background :
FSH (Follicle-stimulating hormone) is a gonadotropin, a glycoprotein polypeptide hormone. It has a functionally indispensable 96 amino acid α subunit that is common to LH, TSH and hCG, in addition to a structurally unique β subunit. FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland and regulates the development, growth, pubertal maturation, and reproductive processes of the body.

Synonyms :
FSH alpha/beta; FSH alphaβ FSH alpha & FSH beta

References & Citations :
(1) (1)Haldar S, Agrawal H, Saha S, Straughn AR, Roy P, Kakar SS. Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells. Int J Biol Sci. 2022 Jan 1;18(2):675-692.

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