Name : Human GPA34/VSIG1 Protein
Product Source :
Recombinant Human GPA34/VSIG1 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Val22-Glu232.[Accession | Q86XK7-1]
Molecular Weight :
The protein has a predicted MW of 24 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human GPA34/VSIG1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human GPA34/VSIG1 is greater than 95% as determined by SEC-HPLC.
Background :
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three alternatively spliced isoforms of mouse Vsig1 during pre- and postnatal development of stomach and potential function of Vsig1 in differentiation of gastric epithelia. VSIG1 is required for the establishment of glandular versus squamous epithelia in the stomach.
Synonyms :
Glycoprotein A34; Gpa34; dJ889N15.1; MGC44287,1700062D20Rik; VSIG1
References & Citations :
(1) Oidovsambuu O, Nyamsuren G, Liu S, Göring W, Engel W, Adham IM. Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia. PLoS One. 2011;6(10):e25908. doi: 10.1371/journal.pone.0025908. Epub 2011 Oct 4. PMID: 21991385; PMCID: PMC3186807.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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