Name : Biotinylated Human Latent TGF beta 3 Protein (Primary Amine Labeling)
Product Source :
Recombinant Biotinylated Human Latent TGF beta 3 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the N-Terminus. It contains Leu24-Ser412.[Accession | P10600-1]
Molecular Weight :
The protein has a predicted MW of 45.9 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in 20mM PBS (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Biotinylated Human Latent TGF beta 3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. ELISA Data Immobilized Human TGF-beta RII at 0.5μg/ml(100μl/well) on the plate. Dose response curve for Biotinylated Human Latent TGF beta 3, His Tag with the EC50 of 0.15μg/ml determined by ELISA.
Background :
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos.
Synonyms :
TGFB3; ARVD; TGF-beta3; TGF-β; TGFβ3; TGFβ
References & Citations :
(1) Okamura T, Morita K, Iwasaki Y, Inoue M, Komai T, Fujio K, Yamamoto K. Role of TGF-β3 in the regulation of immune responses. Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 92):S63-9. Epub 2015 Oct 12. PMID: 26457612.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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