Name : Human TRIB3 Protein

Product Source :
Recombinant Human TRIB3 Protein is expressed from Baculovirus-Insect Cells with GST tag at the N-terminus. It contains Met1-Gly358.[Accession | Q96RU7]

Molecular Weight :
The protein has a predicted MW of 66.14 kDa same as Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :
> 90% as determined by Tris-Bis PAGE

Formulation :
Supplied as 0.22 μm filtered solution in 50mM Tris, 100mM NaCl, 0.5mM Reduced Glutathione, 10% Glycerol, 0.5mM PMSF (pH 8.0).

Reconstitution :

Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Human TRIB3 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.

Background :
Tribbles homolog 3 (TRIB3) is a mammalian gene that is upregulated in response to several types of cell death-inducing cellular stress. The TRIB3 protein is a pseudokinase, a protein kinase-like scaffold with impaired catalytic activity.

Synonyms :
TRB-3; SINK; C20orf97; NIPK; SKIP3; TRB3

References & Citations :
Ord T, Ord T. Mammalian Pseudokinase TRIB3 in Normal Physiology and Disease: Charting the Progress in Old and New Avenues. Curr Protein Pept Sci. 2017;18(8):819-842. doi: 10.2174/1389203718666170406124547. PMID: 28393700.

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