Name : Cynomolgus CEACAM-6/CD66c Protein
Product Source :
Recombinant Cynomolgus CEACAM-6/CD66c Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Gln35-Gly320.[Accession | XP_014979566.2]
Molecular Weight :
The protein has a predicted MW of 32.73 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Cynomolgus CEACAM-6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Cynomolgus CEACAM-6 is greater than 95% as determined by SEC-HPLC.
Background :
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) belongs to the human carcino-embryonic antigen (CEA) family. Numerous lines of studies have indicated that altered expression of CEACAM6 may have a role in carcinogenesis and development.
Synonyms :
CEACAM6; CD66c; CEAL; NCA; CEA
References & Citations :
(1)harma N, Srivastava S, Kern F, et al. CEACAM 6, a novel marker for the diagnosis of Barrett’s esophagus. Dis Esophagus. 2017;30(7):1-5. doi:10.1093/dote/dox026
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