Name : Human AKT2 Protein
Product Source :
Recombinant Human AKT2 Protein is expressed from Baculovirus-Insect Cells with His tag and GST tag at the N-terminus. It contains Met1-Glu481.[Accession | P31751-1]
Molecular Weight :
The protein has a predicted MW of 84.00 kDa. The protein migrates to 70-85 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 10% glycerol (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human AKT2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
Akt2 is a pivotal player in a complex web of signaling pathways controlling cell growth, proliferation, and survival. The deregulation or aberrations of Akt2 have been associated with tumor progression, metastatic spread, and, lastly, chemoresistance.
Synonyms :
Akt-2; PKB beta; PKBB;
References & Citations :
Pereira L, Horta S, Mateus R, Videira MA. Implications of Akt2/Twist crosstalk on breast cancer metastatic outcome. Drug Discov Today. 2015 Sep;20(9):1152-8. doi: 10.1016/j.drudis.2015.06.010. Epub 2015 Jun 29. PMID: 26136161.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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