Product Name: S- (+)-RolipramSubtitle: CAMP-specific PDE4 inhibitorBiological Activity: Biological Activity of S- (+)-RolipramLess active enantiomer of the PDE4 inhibitor rolipram. (R)-(-)-Rolipram also available.SMLES: COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3CAS NO: 863971-19-1Standard In CHIKey: HJORMJIFDVBMOB-GFCCVEGCSA-NGABA Receptor…
Product Name: TrilostaneSubtitle: Biological Activity: SMLES: N#CC1=C(2()O2(C()()C3())(C1())(C()())4()3()(C()()C()()5()O)()5(C()())C()()C4())OCAS NO: 1062368-62-0Standard In CHIKey: KVJXBPDAXMEYOA-CXANFOAXSA-NEAAT2 inhibitorsStandard InChI: InChI=1S/C20H27NO3/c1-18-7-6-14-12(13(18)3-4-15(18)22)5-8-20-17(24-20)16(23)11(10-21)9-19(14,20)2/h12-15,17,22-23H,3-9H2,1-2H3/t12-,13-,14-,15-,17+,18-,19+,20+/m0/s1Typrof Compound: Appearance: Formula: C20H27NO3M.Wt: 329.43General Tips: For obtaining a higher solubility , please warm the…
Product Name: MethotrexateSubtitle: Folate antagonist,inhibits DFHRBiological Activity: Biological Activity of MethotrexateCytotoxic agent. Inhibits thymidylate synthetase and de novo purine synthesis. Potent folic acid antagonist; inhibits dihydrofolate reductase. Also inhibits Ras…
Product Name: AminophyllineSubtitle: Biological Activity: SMLES: CAS NO: 0Standard In CHIKey: FQPFAHBPWDRTLU-UHFFFAOYSA-NCRAC Channel inhibitorsStandard InChI: InChI=1S/2C7H8N4O2.C2H8N2/c2*1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;3-1-2-4/h2*3H,1-2H3,(H,8,9);1-4H2Typrof Compound: Appearance: Formula: C16H24N10O4M.Wt: 420.43General Tips: For obtaining a higher solubility , please warm…
Product Name: MK-8245Subtitle: SCD inhibitor,potent and liver-selectiveBiological Activity: Biological Activity of MK-8245Description MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 values of 1 nM, 3 nM and…
Product Name: OzagrelSubtitle: Thromboxane A2 synthetase inhibitorBiological Activity: SMLES: C1=CC(=CC=C1CN2C=CN=C2)C=CC(=O)OCAS NO: 1187431-43-1Standard In CHIKey: SHZKQBHERIJWAO-AATRIKPKSA-NCFTR inhibitorsStandard InChI: InChI=1S/C13H12N2O2/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15/h1-8,10H,9H2,(H,16,17)/b6-5+Typrof Compound: Appearance: Formula: C13H12N2O2M.Wt: 228.25General Tips: For obtaining a higher solubility ,…
Product Name: DyphyllineSubtitle: Biological Activity: SMLES: CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)OCAS NO: 850664-21-0Standard In CHIKey: KSCFJBIXMNOVSH-UHFFFAOYSA-NCalcium Channel inhibitorsStandard InChI: InChI=1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3Typrof Compound: Appearance: Formula: C10H14N4O4M.Wt: 254.24General Tips: For obtaining a higher solubility , please warm…
Product Name: GimeracilSubtitle: Dihydropyrimidine dehydrogenase inhibitorBiological Activity: SMLES: C1=C(C(=CNC1=O)Cl)OCAS NO: 130641-38-2Standard In CHIKey: ZPLQIPFOCGIIHV-UHFFFAOYSA-NBCRP inhibitorsStandard InChI: InChI=1S/C5H4ClNO2/c6-3-2-7-5(9)1-4(3)8/h1-2H,(H2,7,8,9)Typrof Compound: Appearance: Formula: C5H4ClNO2M.Wt: 145.54General Tips: For obtaining a higher solubility , please…
Product Name: PimobendanSubtitle: Selective PDE3 inhibitor.Ca2+ channel sensitizerBiological Activity: SMLES: CC1CC(=O)NN=C1C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)OCCAS NO: 192185-72-1Standard In CHIKey: GLBJJMFZWDBELO-UHFFFAOYSA-NMembrane Transporter_Ion Channel inhibitorsStandard InChI: InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)Typrof Compound: Appearance: Formula: C19H18N4O2M.Wt: 334.37General Tips: For obtaining a…
Product Name: AGI-5198Subtitle: IDH1 inhibitor against R132 mutant,selective and cell-permeableBiological Activity: Biological Activity of AGI-5198Description AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50…