Product Name: B-Raf inhibitor 1Subtitle: Biological Activity: SMLES: CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6CAS NO: 1449277-10-4Standard In CHIKey: Deubiquitinase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C26H19ClN8M.Wt: 478.94General Tips: For obtaining a higher solubility , please…
Product Name: SB 242235Subtitle: MAPK inhibitorBiological Activity: SMLES: COC1=NC=CC(=N1)C2=C(N=CN2C3CCNCC3)C4=CC=C(C=C4)FCAS NO: 302962-49-8Standard In CHIKey: CRISPR_Cas9 inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C19H20FN5OM.Wt: 353.39General Tips: For obtaining a higher solubility , please…
Product Name: GDC-0623Subtitle: MEK1 inhibitor, potent and ATP-uncompetitiveBiological Activity: Biological Activity of GDC-0623Description GDC-0623 is a potent and ATP-uncompetitive inhibitor of MEK1 with Ki value of 0.13 nM. Targets MEK1…
Product Name: VRT752271Subtitle: ERK1/ERK2 inhibitorBiological Activity: SMLES: CC(C)NC1=NC=C(C(=C1)C2=CNC(=C2)C(=O)NC(CO)C3=CC(=CC=C3)Cl)ClCAS NO: 585543-15-3Standard In CHIKey: CDK inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C21H22Cl2N4O2M.Wt: 433.33General Tips: For obtaining a higher solubility , please warm…
Product Name: Refametinib R enantiomerSubtitle: MEK1/2 allosteric inhibitorBiological Activity: SMLES: COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)FCAS NO: 1421373-66-1Standard In CHIKey: Casein Kinase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C19H20F3IN2O5SM.Wt: 572.34General Tips: For obtaining a higher…
Product Name: OTS964Subtitle: TOPK inhibitor,potent and selectiveBiological Activity: SMLES: C(CN(C)C)C1=CC=C(C2=C(O)C=CC3=C2C(C=CS4)=C4C(N3)=O)C=C1CAS NO: 1218778-77-8Standard In CHIKey: Aurora Kinase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C22H22N2O2SM.Wt: 378.49General Tips: for obtaining a higher concentration:…
Product Name: OTS514Subtitle: TOPK inhibitor,highly potentBiological Activity: SMLES: NC(C)C1=CC=C(C2=C(O)C=CC3=C2C(C=CS4)=C4C(N3)=O)C=C1CAS NO: 1216941-48-8Standard In CHIKey: ATM_ATR inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C20H18N2O2SM.Wt: 350.43General Tips: For obtaining a higher solubility , please…
Product Name: PF-04880594Subtitle: RAF inhibitorBiological Activity: Biological Activity of PF-04880594Description PF-04880594 is an inhibitor of RAF with IC50 values of 0.19 nM/0.13 nM and 0.39 nM for BRAF/BRAFV599E and c-RAF,…
Product Name: LY3009120Subtitle: pan-RAF and RAF dimer inhibitorBiological Activity: SMLES: CC1=NC2=NC(NC)=NC=C2C=C1C3=CC(NC(NCCC(C)(C)C)=O)=C(F)C=C3CCAS NO: 1604810-83-4Standard In CHIKey: Cell Cycle_DNA Damage inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C23H29FN6OM.Wt: 424.51General Tips: For obtaining a…
Product Name: PD 169316Subtitle: P38 MAPK inhibitorBiological Activity: SMLES: C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)(=O)CAS NO: 1025015-40-0Standard In CHIKey: ULK inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C20H13FN4O2M.Wt: 360.34General Tips: For obtaining a higher solubility ,…