Nociceptin (1-13)NH2
Product Name: Nociceptin (1-13)NH2Subtitle: Biological Activity: Biological Activity of Nociceptin (1-13)NH2Bioactive metabolite of nociceptin and potent agonist for the ORL1 receptor (pEC50 = 7.9 in mouse vas deferens, Ki =…
RS 100329 hydrochloride
Product Name: RS 100329 hydrochlorideSubtitle: Biological Activity: Biological Activity of RS 100329 hydrochlorideSubtype-selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors). Displays 126- and 50-fold selectivity over human…
[Nphe1]Nociceptin(1-13)NH2
Product Name: Nociceptin(1-13)NH2Subtitle: Biological Activity: Biological Activity of Nociceptin(1-13)NH2Selective and competitive nociceptin receptor antagonist, devoid of any agonist activity. Binds selectively to recombinant nociceptin receptors (pKi = 8.4), and competitively…
Nociceptin (1-7)
Product Name: Nociceptin (1-7)Subtitle: Biological Activity: Biological Activity of Nociceptin (1-7)Bioactive metabolite of nociceptin. Antagonizes nociceptin-induced hyperalgesia, with no effect on nociceptin-induced analgesia.SMLES: O(C)(C(NCC(N(C(O)=O)C)=O)=O)NC((CC1=CC=CC=C1)NC(CNC(CNC((CC2=CC=CC=C2)N)=O)=O)=O)=OCAS NO: Standard In CHIKey: Neprilysin inhibitorsStandard…
Ac-RYYRIK-NH2
Product Name: Ac-RYYRIK-NH2Subtitle: Biological Activity: Biological Activity of Ac-RYYRIK-NH2High affinity ligand for the NOP site (Ki = 1.5 nM). Antagonizes nociceptin-stimulated GTP binding in rat brain and the chronotropic effect…
ZD 7155 hydrochloride
Product Name: ZD 7155 hydrochlorideSubtitle: Biological Activity: Biological Activity of ZD 7155 hydrochlorideA potent and selective competitive antagonist for the angiotensin II type 1 (AT1) receptor. Displaces -angiotensin II binding…
FR 139317
Product Name: FR 139317Subtitle: Biological Activity: Biological Activity of FR 139317A highly potent and selective ETA endothelin receptor antagonist (Ki values are 1 nM and 7.3 μM at ETA and…
Nocistatin (human)
Product Name: Nocistatin (human)Subtitle: Biological Activity: Biological Activity of Nocistatin (human)Human putative counterpart of nocistatin (bovine). Blocks nociceptin-induced allodynia and hyperalgesia.SMLES: N/ACAS NO: 315702-99-9Standard In CHIKey: Mineralocorticoid Receptor inhibitorsStandard InChI:…
[Ala1,3,11,15]-Endothelin
Product Name: -EndothelinSubtitle: Biological Activity: Biological Activity of -EndothelinSelective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing -ET-1 from ETB and ETA receptors respectively).SMLES: CAS…
IRL-1038
Product Name: IRL-1038Subtitle: Biological Activity: Biological Activity of IRL-1038ETB endothelin receptor antagonist.SMLES: N/ACAS NO: 1819986-22-5Standard In CHIKey: OETKRDJJNWJFOP-PFAVPODXSA-NLXR inhibitorsStandard InChI: InChI=1S/C68H92N14O15S2/c1-9-37(7)56(66(94)78-52(68(96)97)27-41-30-71-46-19-15-14-18-44(41)46)82-67(95)57(38(8)10-2)81-63(91)51(29-54(84)85)76-59(87)47(24-35(3)4)73-62(90)50(28-42-31-70-34-72-42)75-64(92)53-33-99-98-32-45(69)58(86)80-55(36(5)6)65(93)77-49Typrof Compound: Appearance: Formula: C68H92N14O15S2M.Wt: 1410General Tips: For obtaining a…