Name : Human FSH alpha&beta Protein
Product Source :
Recombinant Human FSH alpha&beta Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Ala25-Ser116 (FSH alpha) & Asn19-Glu129 (FSH beta).[Accession | P01215(FSH alpha)&P01225 (FSH beta)]
Molecular Weight :
The protein has a predicted MW of 10.20 kDa (FSH alpha) and 39.2 kDa (FSH beta). Due to glycosylation, the protein migrates to 25-30 kDa (FSH alpha) and 50-60 kDa (FSH beta) based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human FSH alpha&beta on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human FSH alpha&beta is greater than 95% as determined by SEC-HPLC.
Background :
FSH (Follicle-stimulating hormone) is a gonadotropin, a glycoprotein polypeptide hormone. It has a functionally indispensable 96 amino acid α subunit that is common to LH, TSH and hCG, in addition to a structurally unique β subunit. FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland and regulates the development, growth, pubertal maturation, and reproductive processes of the body.
Synonyms :
FSH alpha/beta; FSH alphaβ FSH alpha & FSH beta
References & Citations :
(1) (1)Haldar S, Agrawal H, Saha S, Straughn AR, Roy P, Kakar SS. Overview of follicle stimulating hormone and its receptors in reproduction and in stem cells and cancer stem cells. Int J Biol Sci. 2022 Jan 1;18(2):675-692.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
DEP-1/CD148 Protein
NELL2 Protein
Popular categories:
Serpin B4
Insulin Receptor Family