Name : Human APLP2 Protein
Product Source :
Recombinant Human APLP2 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Gly32-Ser692.[Accession | Q06481-1]
Molecular Weight :
The protein has a predicted MW of 77.16 kDa. Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human APLP2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human APLP2 is greater than 95% as determined by SEC-HPLC.
Background :
Amyloid β precursor-like protein 2 (APLP2) has been determined to serve an important role in the progression of a number of cancer types. APLP2 expression was significantly associated with disease-specific survival (P<0.001). APLP2 may be used to potentially predict patient prognosis, and to guide clinical diagnosis and treatment in CCRCC.
Synonyms :
APPH; CDEBP; CDEI box-binding; APPL2; YWK-II;
References & Citations :
Gao L, Zhao H, Zhang D, Zhou C, Wang H, Ren C, Liu Y, Xia Y, Shi B. Role of APLP2 in the prognosis and clinicopathology of renal cell carcinoma. Oncol Lett. 2019 Jan;17(1):508-513. doi: 10.3892/ol.2018.9577. Epub 2018 Oct 15. PMID: 30655794; PMCID: PMC6313182.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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