Product Name: ABT-046Subtitle: DGAT-1 inhibitor,potent and selectiveBiological Activity: SMLES: CAS NO: 1675203-84-5Standard In CHIKey: CCR inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C20H22N4O2M.Wt: 350.41General Tips: For obtaining a higher solubility ,…
Product Name: Leucovorin CalciumSubtitle: Derivative of folic acidBiological Activity: SMLES: C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O))C(=O).O.O.O.O.O.CAS NO: 1396257-94-5Standard In CHIKey: DZNHRKNLTYYMQA-ZIGBGYJWSA-NCaSR inhibitorsStandard InChI: InChI=1S/C20H23N7O7.Ca.5H2O/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;;;;;;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);;5*1H2/t12?,13-;;;;;;/m0……/s1Typrof Compound: Appearance: Formula: C21H25CaN7O7.5H2OM.Wt: 601.58General Tips: For obtaining a higher solubility…
Product Name: 17-DMAG (Alvespimycin) HClSubtitle: Hsp90 inhibitorBiological Activity: Biological Activity of 17-DMAG (Alvespimycin) HClWater-soluble analog of 17-AAG and geldanamycin. Binds the ATP binding site of Hsp90 and inhibits its chaperone…
Product Name: PosaconazoleSubtitle: Sterol C14ɑ demethylase inhibitorBiological Activity: Biological Activity of PosaconazoleDescription Posaconazole is an inhibitor of C14ɑ demethylase with IC50 value of 0.25 nM. Targets C14ɑ demethylase IC50 0.25…
Product Name: VinpocetineSubtitle: PDE inhibitorBiological Activity: Biological Activity of Vinpocetine Phosphodiesterase inhibitor, selective for PDE1 (IC50 = 21 μM). Also blocks voltage-gated Na+ channels.SMLES: CCOC(=O)C1=C2(CC)CCCN3CCc4c5ccccc5n1c423CAS NO: 700874-72-2Standard In CHIKey: DDNCQMVWWZOMLN-IRLDBZIGSA-NAngiotensin…
Product Name: SimvastatinSubtitle: HMGCR (HMG-CoA reductase) inhibitorBiological Activity: Biological Activity of Simvastatin HMG-CoA reductase inhibitor; decreases levels of low density lipoprotein. Has multiple biological effects including bone formation stimulation, inhibition…
Product Name: RotenoneSubtitle: inhibitor of the mitochondrial complex I electron transport chainBiological Activity: Biological Activity of Rotenone Mitochondrial electron transport chain inhibitor (IC50 = 1.7 – 2.2 μM at complex…
Product Name: RoflumilastSubtitle: PDE-4 inhibitorBiological Activity: Biological Activity of Roflumilast 1. Roflumilast is a phosphodiesterase 4 inhibitor that may improve lung function and reduce the frequency of exacerbations in patients…
Product Name: Rasagiline mesylateSubtitle: Irreversible MAO-B inhibitorBiological Activity: Biological Activity of Rasagiline mesylate Selective irreversible MAO-B inhibitor. Displays antiParkinsonian activity; exhibits neuroprotective and antiapoptotic activity against several neurotoxins in cell…
Product Name: Pemetrexed disodiumSubtitle: TS, DHFR,GARFT and AICARFT inhibitorBiological Activity: Biological Activity of Pemetrexed disodium 1. Pemetrexed disodium activates MEK/ERK-dependent cyto-protective autophagy, and inhibition of this pathway potentiates Pemetrexed disodiums…