Product Name: PKA inhibitor fragment (6-22) amideSubtitle: PKA inhibitorBiological Activity: Biological Activity of PKA inhibitor fragment (6-22) amidePotent inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM); derived from…
Product Name: GLPG0634Subtitle: JAK1 inhibitor, potent and selectiveBiological Activity: Biological Activity of GLPG0634Description GLPG0634 is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116…
Product Name: FLLL32Subtitle: STAT3 inhibitorBiological Activity: SMLES: COC1=C(OC)C=C(/C()=C()/C(C2(C(/C()=C()/C3=CC(OC)=C(OC)C=C3)=O)CCCCC2)=O)C=C1CAS NO: 287194-40-5Standard In CHIKey: NF-κB_Signaling_Compound_Library inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C28H32O6M.Wt: 464.55General Tips: For obtaining a higher solubility , please warm…
Product Name: AZD3759Subtitle: EGFR inhibitor，oral activeBiological Activity: SMLES: CAS NO: 941678-49-5Standard In CHIKey: Neuronal_Signaling_Compound_Library inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C22H23ClFN5O3M.Wt: 459.90General Tips: For obtaining a higher solubility , please…
Product Name: AZ5104Subtitle: EGFR inhibitorBiological Activity: SMLES: CAS NO: 1419949-20-4Standard In CHIKey: Natural_Product_Library_ inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C27H31N7O2M.Wt: 485.58General Tips: For obtaining a higher solubility , please warm…
Product Name: HO-3867Subtitle: STAT3 inhibitor, selectiveBiological Activity: SMLES: O=C(/C(CN(CC1=CC(C)(C)N(O)C1(C)C)C/2)=C/C3=CC=C(F)C=C3)C2=CC4=CC=C(F)C=C4CAS NO: 936563-96-1Standard In CHIKey: Metabolism/Protease_Compound_Library inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C28H30F2N2O2M.Wt: 464.55General Tips: For obtaining a higher solubility , please…
Product Name: TCS-PIM-1-4aSubtitle: Pim inhibitorBiological Activity: SMLES: O=C(NC(S/1)=O)C1=CC2=CC=CC(C(F)(F)F)=C2CAS NO: 108212-75-5Standard In CHIKey: MAPK_Compound_Library inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C11H6F3NO2SM.Wt: 273.23General Tips: For obtaining a higher solubility , please warm…
Product Name: NiclosamideSubtitle: Biological Activity: Biological Activity of NiclosamideInhibitor of the STAT3 signaling pathway; inhibits the activation, nuclear translocation and transactivation of STAT3. Displays selectivity for STAT3 over STAT1, STAT5,…
Product Name: IcotinibSubtitle: EGFR tyrosine kinase inhibitorBiological Activity: SMLES: C1=C2OC()()C()()OC()()C()()OC()()C()()OC2=C()C3=NC()=NC(N()C4=C()C()=C()C(C#C)=C4)=C31CAS NO: 1604810-84-5Standard In CHIKey: JAK/STAT_Compound_Library inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C22H21N3O4M.Wt: 391.42General Tips: For obtaining a higher solubility ,…
Product Name: OSI-420Subtitle: EGFR inhibitorBiological Activity: Biological Activity of OSI-420Description OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM). Targets EGFR IC50SMLES: COCCOC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCO.ClCAS NO: 1255580-76-7Standard…