Product Name: BMS-911543Subtitle: JAK2 inhibitor,selective small moleculeBiological Activity: Biological Activity of BMS-911543Description BMS-911543 is a selective small-molecule inhibitor of Janus tyrosine kinase 2 (JAK2) with IC50 value of 1 nM.…
Product Name: ZM 39923 HClSubtitle: JAK3 inhibitor,potent and selectiveBiological Activity: Biological Activity of ZM 39923 HClDescription ZM 39923 HCl is a potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3)…
Product Name: WHI-P154Subtitle: JAK3 inhibitorBiological Activity: Biological Activity of WHI-P154JAK3 inhibitor (IC50 = 1.8 μM) that displays no activity at JAK1 or JAK2. Inhibits STAT1 activation, iNOS expression and NO…
Product Name: WP1066Subtitle: JAK2/STAT3 inhibitor,cell-permeableBiological Activity: Biological Activity of WP1066Description WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells.…
Product Name: AG-490Subtitle: JAK2/EGFR inhibitorBiological Activity: Biological Activity of AG-490Selective inhibitor of EGF receptor tyrosine kinase (IC50 values are 2 and 13.5 μM for EGFR and ErbB2 respectively). Inhibitor of…
Product Name: Lapatinib DitosylateSubtitle: EGFR/HER2 inhibitor,potent and selectiveBiological Activity: Biological Activity of Lapatinib DitosylateDescription Lapatinib Ditosylate (GW572016, GW2016) is a potent inhibitor of EGFR and ErbB2 with IC50 of 10.8…
Product Name: Icotinib HydrochlorideSubtitle: EGFR inhibitor,potent and specificBiological Activity: Biological Activity of Icotinib HydrochlorideDescription Icotinib Hydrochloride is a potent and specific inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinases…
Product Name: Gefitinib hydrochlorideSubtitle: Potent EGFR inhibitorBiological Activity: SMLES: COc1cc2c(cc1OCCCN3CCOCC3)c(ncn2)Nc4ccc(c(c4)Cl)F.ClCAS NO: 955977-50-1Standard In CHIKey: beta)-catenin inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C22H25Cl2FN4O3M.Wt: 483.36General Tips: For obtaining a higher solubility ,…
Product Name: ErlotinibSubtitle: EGFR tyrosine kinase inhibitorBiological Activity: SMLES: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOCCAS NO: 1204669-58-8Standard In CHIKey: AAKJLRGGTJKAMG-UHFFFAOYSA-NYAP inhibitorsStandard InChI: InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)Typrof Compound: Appearance: Formula: C22H23N3O4M.Wt: 393.44General Tips: For obtaining a higher solubility ,…
Product Name: CO-1686 (AVL-301)Subtitle: EGFR inhibitorBiological Activity: Biological Activity of CO-1686 (AVL-301)Description CO-1686 is an irreversible and orally delivered inhibitor of EGFR with IC50 values of 21.5 nM and 303.3…