PF-543
Product Name: PF-543Subtitle: SphK1 inhibitor,cell-permeate,potent and selectiveBiological Activity: Biological Activity of PF-543Description PF-543 is a novel cell-permeable inhibitor of SphK1 with Ki value of 3.6 nM. Targets SphK1 IC50 3.6…
Pentostatin
Product Name: PentostatinSubtitle: Irreversible adenosine deaminase inhibitorBiological Activity: Biological Activity of PentostatinIrreversible inhibitor of adenosine deaminase (Ki = 2.5 pM). Anticancer agent.SMLES: C1C(C(OC1N2C=NC3=C2NC=NCC3O)CO)OCAS NO: 266359-83-5Standard In CHIKey: FPVKHBSQESCIEP-JQCXWYLXSA-NNeuronal Signaling inhibitorsStandard…
PD 123319 ditrifluoroacetate
Product Name: PD 123319 ditrifluoroacetateSubtitle: Angiotensin AT2 receptor antagonistBiological Activity: SMLES: CC1=C(C=CC(=C1)CN2C=NC3=C2CC(N(C3)C(=O)C(C4=CC=CC=C4)C5=CC=CC=C5)C(=O)O)N(C)C.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)OCAS NO: 700874-71-1Standard In CHIKey: Xanthine Oxidase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C35H34F6N4O7M.Wt: 736.66General Tips: For obtaining a…
PB-22
Product Name: PB-22Subtitle: Synthetic cannabinoidBiological Activity: SMLES: CCCCCN1C=C(C2=CC=CC=C21)C(=O)OC3=CC=CC4=C3N=CC=C4CAS NO: 1029044-16-3Standard In CHIKey: Tyrosinase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C23H22N2O2M.Wt: 358.43General Tips: For obtaining a higher solubility , please warm…
Otenabant
Product Name: OtenabantSubtitle: CB1 receptor antagonistBiological Activity: SMLES: CCNC1(CCN(CC1)C2=NC=NC3=C2N=C(N3C4=CC=C(C=C4)Cl)C5=CC=CC=C5Cl)C(=O)NCAS NO: 630420-16-5Standard In CHIKey: Tryptophan Hydroxylase inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C25H25Cl2N7OM.Wt: 510.42General Tips: For obtaining a higher solubility ,…
Orteronel
Product Name: OrteronelSubtitle: For castration-resistant prostate cancer, clinical candidateBiological Activity: Biological Activity of OrteronelDescription TAK-700 (Orteronel) is a potent and highly selective inhibitor of human and rat 17,20-lyase with IC50…
ONO-AE3-208
Product Name: ONO-AE3-208Subtitle: EP4 receptor inhibitor,high affinity and selectiveBiological Activity: Biological Activity of ONO-AE3-208High affinity and selective EP4 receptor antagonist (Ki values are 1.3, 30, 790 and 2400 nM for…
Olmesartan
Product Name: OlmesartanSubtitle: Biological Activity: Biological Activity of OlmesartanPotent angiotensin II type I (AT1) receptor antagonist (IC50 = 6.7 nM at hAT1 receptors). Improves cognitive function in a mouse model…
NPS-2143 hydrochloride
Product Name: NPS-2143 hydrochlorideSubtitle: Calcium ion-sensing receptor antagonistBiological Activity: Biological Activity of NPS-2143 hydrochlorideSelective Ca2+-sensing receptor antagonist. Blocks increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in…
Nepicastat
Product Name: NepicastatSubtitle: Inhibitor of dopamine-β-hydroxylase,potent and selectiveBiological Activity: Biological Activity of NepicastatDescription Nepicastat is a selective inhibitor of dopamine β-hydroxylase (DBH) with IC50 value of 9 nM. Targets DBH…